An 84-year-old woman disappears from her home, blood found on the doorstep. Foreign DNA is discovered inside the house, but it’s a mixed sample. And more than a month later, investigators still don’t have a suspect.

In this episode of “The Truth of the Matter Podcast,” Natasha Zouves sits down with one of the most prominent genetic genealogists in the world, CeCe Moore, the forensic expert who has helped solve more than 300 cases using DNA.
Moore breaks down what investigators are really dealing with in the Nancy Guthrie disappearance, and why the DNA evidence may be far more complicated than the public realizes.
Among the revelations in this interview:
Moore believes the technology needed to separate the mixed DNA sample may not exist yet
Why police cannot simply search the largest 23andMe or Ancestry databases
The loophole investigators used in the Bryan Kohberger / Idaho murders case that no longer exists
Why Moore believes investigators should re-swab the Guthrie home right now
And why she believes the case could turn on the discovery of a second crime scene
Investigative genetic genealogy helped identify the Golden State Killer and helped lead police to Bryan Kohberger in the Idaho student murders. Moore believes genetic genealogy will solve this case — and talks about the path to get there.
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🕊️ LAST CRY FOR HELP FROM THE MOUNTAINS — WESTON’S PHONE WENT SILENT FOREVER Auburn University environmental engineering student James “Weston” Higginbotham, 20, made one final attempt to reach out from his phone… then total silence.
James ‘Weston’ Higginbotham’s mom claimed that she and her son had an argument over her use of ChatGPT on their vacation before he vanished and later died. Updated on: Jun 07, 2026 1:27 PM IST BySumanti Sen The mother of Auburn University student James ‘Weston’ Higginbotham, 20, claimed that she and her son had an argument […]
😢 PHONE PINGED ONE LAST TIME… THEN WESTON WAS GONE FOREVER 20-year-old Auburn University student James “Weston” Higginbotham’s phone sent its final signal from the mountains of Japan before going completely silent.
James ‘Weston’ Higginbotham’s mom claimed that she and her son had an argument over her use of ChatGPT on their vacation before he vanished and later died. Updated on: Jun 07, 2026 1:27 PM IST BySumanti Sen The mother of Auburn University student James ‘Weston’ Higginbotham, 20, claimed that she and her son had an argument […]
🚨 FINAL DISTRESS SIGNAL FROM HIS PHONE BEFORE ETERNAL SILENCE 😭 Just 20 years old… Auburn University environmental engineering student James “Weston” Higginbotham made one last desperate attempt to reach out from the mountains of Kyoto — then his phone went completely silent.
James ‘Weston’ Higginbotham’s mom claimed that she and her son had an argument over her use of ChatGPT on their vacation before he vanished and later died. Updated on: Jun 07, 2026 1:27 PM IST BySumanti Sen The mother of Auburn University student James ‘Weston’ Higginbotham, 20, claimed that she and her son had an argument […]
💥 DEVASTATING FINAL MOMENTS VIDEO JUST PLAYED IN COURT
After a 2025 high school track meet in Frisco, Texas, ended with one student dead and another accused of murder, Karmelo Anthony, then 17, was indicted on first-degree murder in the fatal stabbing of Austin Metcalf, 17. Social media posts about the death divided the case into racial lines, sparking national outrage. Anthony, who is being […]
🩸 THE CHILLING LAST MOMENTS OF AUSTIN METCALF CAUGHT ON CAMERA
After a 2025 high school track meet in Frisco, Texas, ended with one student dead and another accused of murder, Karmelo Anthony, then 17, was indicted on first-degree murder in the fatal stabbing of Austin Metcalf, 17. Social media posts about the death divided the case into racial lines, sparking national outrage. Anthony, who is being […]
🔴 VIDEO OF AUSTIN METCALF’S FINAL BREATHS JUST HIT THE COURTROOM
After a 2025 high school track meet in Frisco, Texas, ended with one student dead and another accused of murder, Karmelo Anthony, then 17, was indicted on first-degree murder in the fatal stabbing of Austin Metcalf, 17. Social media posts about the death divided the case into racial lines, sparking national outrage. Anthony, who is being […]
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