Savannah Guthrie’s sister, Annie Guthrie, was the last person to see their mom, Nancy Guthrie, before she was reported missing in Arizona, Us Weekly can confirm.

Pima County Sheriff Chris Nanos exclusively spoke to Us on Monday, February 2, revealing what police know about what happened in the hours leading up to her disappearance.

“We have a start point,” Nanos said. “The family took her home from dinner at about 9:30 to 9:45 [p.m.]” on Saturday, January 31. “So we would back that up to even say 9 or 8:30 p.m. to start looking.”

Nanos confirmed that Annie, Savannah’s older sister, was the last person to see Nancy, 84, prior to her reported disappearance. (Nancy shared daughters Annie and Savannah, 54, and son Camron Guthrie with late husband Charles Guthrie, who died after a heart attack at the age of 49.)

Nancy Guthrie, Savannah Guthrie, Annie Guthrie. Courtesy of Savannah Guthrie/Instagram

The sheriff noted that Annie didn’t raise any “red flags” about her mother’s behavior during their last interaction.

According to Nanos, Nancy’s family members “weren’t alerted to her [missing] until about 11 in the morning,” the following day, while police weren’t called until 12:15 p.m. on Sunday, February 1. As a result, officials are investigating a timeline “anywhere from 9:30 p.m. to 11 [a.m.]” as the window of when Nancy went missing.

“This is an 84-year-old lady who is safe in her own home asleep, and she is taken. That should never happen,” Nanos told Us, noting that Savannah didn’t “raise any concerns” about her mother’s health prior to her disappearance.

Savannah Guthrie, Nancy Guthrie, Annie Guthrie. Courtesy of Savannah Guthrie/Instagram

News broke on Sunday that Nancy’s whereabouts were unknown after officials received a 911 call that morning from a concerned family member.

“This is very concerning to us. We don’t typically get the sheriff out at a scene like this. But it’s very concerning what we’re learning from the house,” Nanos said in a press conference on Sunday regarding the case. “And so we’ll just continue. The detective’s homicide team is out right now looking at the scene as well.”

He explained, “We’ve pretty much just thrown everything at this that we can,” adding that Nancy “is not of good physical health, and so naturally that’s a great concern.”

Nanos later added at the press conference that Nancy has “no cognitive issues at all.”

“She’s very alert, she’s of good, sound mind,” he shared, but pointed out that Nancy is “not in good” physical health. “I hope we find her safe and sound, but we can’t ignore what’s in front of us.”

Nanos confirmed that law enforcement was “not ruling out” foul play and had formally launched a criminal investigation into Nancy’s disappearance.

During a second press conference, authorities revealed that due to the crime scene — Nancy’s home in Tucson, Arizona — they believe she “didn’t leave on her own.”

The police added that they were looking at Nancy’s case not as “a search mission as much” as a crime.

On Monday, Savannah was noticeably absent from the Today show — she is currently in Arizona with her loved ones amid the search for her mother. In her absence, her fellow anchors shared a statement on her and her family’s behalf.

“We want to get right to what is a deeply personal story for us,” coanchor Craig Melvin said during the broadcast. “Nancy Guthrie, Savannah’s beloved mother, has been reported missing in Arizona.”

He and Sheinelle Jones then read Savannah’s statement: “On behalf of our family, I want to thank everyone for the thoughts, prayers, and messages of support. Right now, our focus remains on the safe return of our dear mom. We thank law enforcement for their hard work on this case and encourage anyone with information to contact the Pima County Sheriff’s Department.”

Nancy Guthrie, Savannah Guthrie. Courtesy of Savannah Guthrie/Instagram

Jenna Bush Hager also discussed Savannah’s mother’s disappearance on Today With Jenna & Sheinelle on Monday. She revealed that Nancy “takes daily medication” that she needs “for survival,” adding to the urgency in which they hope she is found.

Sheriff Nanos told Us on Tuesday that after speaking with Nancy’s medical team authorities “know the med she needs and going without her meds … can be fatal. Twenty-four hours later, time is of the essence here.”

Bush Hager, 44, meanwhile, told her viewers on Monday, “We are thinking of our dearest, dearest Savannah and her whole family right now. Our prayers obviously go out to Savannah.”

As the search continues, one of Nancy’s neighbors spoke with Us about what has transpired in their community since police began investigating the case.

“There were a lot of dark vans with blacked-out windows,” Morgan Brown, who lives “a quarter of a mile up the street” from Nancy, exclusively told Us on Monday. “There were a lot of cop cars there at first, and then it was vans, so I assumed that maybe they came across something.”

Brown recalled police having a helicopter “up looking for her” on Sunday, noting there are “no sidewalks in our neighborhood. You just walk on the street and then there’s desert, so [they] thought she walked off into the desert or something, but she walks with a cane, so I can’t imagine why she would do that.”

Brown noted that authorities asked anyone with Ring cameras to check their footage “to see if anything popped up out of the ordinary.” He added that hadn’t “heard that anyone found anything” on their videos, and neither did he.

As the investigation into the disappearance of Nancy Guthrie, the 84-year-old mother of NBC Today show co-anchor Savannah Guthrie, deepens into a full-scale criminal probe, new and unsettling neighbor accounts have surfaced. Multiple residents in the Catalina Foothills neighborhood near Tucson, Arizona, claim to have overheard or witnessed what they describe as a prolonged argument between Nancy and her daughter Savannah two days before Nancy vanished—on or around Friday, January 30, 2026. Sources familiar with the whispers circulating in the close-knit community report that the exchange grew heated, lasting “a long time,” before one neighbor allegedly heard Nancy’s final words in the dispute: a phrase so eerie it reportedly “sent chills down everyone’s spine.”

While authorities have not publicly confirmed or addressed these specific claims—maintaining tight control over details to safeguard the case—the rumors have spread rapidly through local social media groups, neighborhood chats, and anonymous tips to media outlets. No direct audio, video, or verifiable witness statements have been released tying the alleged argument to the abduction theory, but the timing has raised eyebrows among those following the case closely. Investigators continue to treat the home as an active crime scene, with evidence including a manually disabled security alarm at 12:50 a.m. Sunday, a damaged rear window from hard impact, traces of blood, DNA samples, forced entry indicators, and Nancy’s essential belongings (fully charged phone, Apple Watch, wallet, keys, car, and critical medication) left behind.

Nancy was last seen safely at home around 9:30–9:45 p.m. Saturday, January 31, after family—including possibly Savannah or siblings—dropped her off following dinner. Her pacemaker stopped syncing with connected devices around 2:00 a.m. Sunday, a detail interpreted as the moment she was removed beyond short-range Bluetooth range. A neighbor’s overlooked camera later captured a dark, unfamiliar SUV moving slowly near the entrance during the overnight window, prompting police to pursue vehicle tracking and GPS leads.

Pima County Sheriff Chris Nanos has been direct: “I believe she was abducted, yes. She didn’t walk from there. She didn’t go willingly.” He described Nancy as “sharp as a tack” with no cognitive issues, limited to walking about 50 yards unaided, and dependent on daily medication that could prove fatal without prompt administration. Homicide detectives are involved, with FBI assistance for potential kidnapping elements and U.S. Customs and Border Protection support given Arizona’s location.

The alleged argument claims add a layer of personal tension speculation, though no official link has been established. Savannah Guthrie, who has long spoken warmly of her mother’s role as a pillar of strength and faith—raising her and siblings after their father’s death when Savannah was 16—has remained in Arizona, focused on the search. Her public statements emphasize gratitude for prayers and a singular goal: “Bring her home.” She has paused Today appearances, including planned Winter Olympics duties, to support family efforts.

Community members describe the Catalina Foothills as safe and serene, making any internal family discord or external intrusion deeply shocking. Neighbors continue reviewing surveillance, with authorities urging tips on unusual activity Friday through Sunday, especially vehicles like the dark SUV or people near the home.

A $2,500 reward via 88-CRIME stands for information leading to Nancy’s safe return or an arrest. The tip line (520-351-4900) remains open. Time is critical—every hour without medication heightens risks.

Nationwide, support pours in amid these chilling whispers and mounting evidence. The case underscores vulnerabilities for elderly residents and the emotional toll on families in the public eye. Prayers persist for Nancy’s swift, safe reunion, as investigators chase every lead—including these neighbor accounts—to resolve the nightmare.